Preparation of a series of highly hindered secondary amines, including bis (triethylcarbinyl) amine

IE Kopka, ZA Fataftah, MW Rathke

Index: Kopka, Ihor E.; Fataftah, Zacharia A.; Rathke, Michael W. Journal of Organic Chemistry, 1980 , vol. 45, # 23 p. 4616 - 4622

Full Text: HTML

Citation Number: 53

Abstract

A series of highly branched secondary amines was prepared by coupling propargylamines with propargyl chlorides. Hydrogenation of the resultant dipropargylamines was accomplished with Raney nickel in the presence of potassium hydroxide. The resultant amines, including bis (triethylcarbinyl) amine, are among the most hindered secondary amines reported to date. The pK, values of the conjugate acids of the series of secondary ...