Chemical Communications

Toluene derivatives as simple coupling precursors for cascade palladium-catalyzed oxidative C–H bond acylation of acetanilides

Y Wu, PY Choy, F Mao, FY Kwong

Index: Wu, Yinuo; Choy, Pui Ying; Mao, Fei; Kwong, Fuk Yee Chemical Communications, 2013 , vol. 49, # 7 p. 689 - 691

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Citation Number: 96

Abstract

A palladium-catalyzed cascade cross-coupling of acetanilide and toluene for the synthesis of ortho-acylacetanilide is described. Toluene derivatives can act as effective acyl precursors (upon sp3-C–H bond oxidation by a Pd/TBHP system) in the oxidative coupling ...