Tetrahedron Letters

A novel synthesis of substituted naphthalenes via Claisen rearrangement and RCM reaction

KS Huang, EC Wang

Index: Huang, Keng-Shiang; Wang, Eng-Chi Tetrahedron Letters, 2001 , vol. 42, # 35 p. 6155 - 6157

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Citation Number: 68

Abstract

A novel synthesis of substituted naphthalenes was studied. Starting from isovanillin, basing on Claisen rearrangement and ring-closing metathesis (RCM), a series of 1-alkoxy-2- methoxynaphthalenes and 1-alkoxy-2-methoxy-8-methylnaphthalenes together with a series

~90%

~89%

~79%

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