Screening Multicomponent Reactions for X-Linked Inhibitor of Apoptosis-Baculoviral Inhibitor of Apoptosis Protein Repeats Domain Binder

I Monfardini, JW Huang, B Beck, JF Cellitti…

Index: Kolb, Juergen; Beck, Barbara; Doemling, Alexander Tetrahedron Letters, 2002 , vol. 43, # 39 p. 6897 - 6901

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Citation Number: 12

Abstract

We report a second example of a general reaction screening approach to discover low molecular weight inhibitors of protein protein interactions. On the basis of the known pharmacophore model of SMAC mimetics, we predicted several inhibitors based on four