Tetrahedron

Chemoselective reduction of azides catalyzed by molybdenum xanthate by using phenylsilane as the hydride source

MR Maddani, SK Moorthy, KR Prabhu

Index: Maddani, Mahagundappa R.; Moorthy, Saravana K.; Prabhu, Kandikere R. Tetrahedron, 2010 , vol. 66, # 1 p. 329 - 333

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Citation Number: 37

Abstract

A chemoselective, neutral, and efficient strategy for the reduction of azides to corresponding amines catalyzed by dioxobis (N, N,-diethyldithiocarbamato) molybdenum complex (1, MoO2 [S2CNEt2] 2) in the presence of phenylsilane is discovered. This chemoselective reduction strategy tolerates a variety of reducible functional groups.