The enantiomers of a series of methoxy-and alkyl-substituted phenylisopropylamines were prepared by low-pressure reduction of imines formed by reaction of the appropriate phenylacetones with either (+)-or (-)-a-methylbenzylamine, followed by hydrogenolysis of the hydrochlorides of the resulting N-(a-phenethy1) phenylisopropylamines. Values of [a] D are reported and enantiomeric purities were-in the range 96-99%. Overall yields ranged ...
