Synthesis and inclusion properties study of some mono 6-amino β-cyclodextrin dimers bridged by N, N-succinyldiamide linkers

C Hocquelet, CK Jankowski, AL Pelletier…

Index: Hocquelet, Celine; Jankowski, Christopher K.; Pelletier, Andre Lucien; Tabet, Jean-Claude; Lamouroux, Christine; Berthault, Patrick Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2011 , vol. 69, # 1-2 p. 75 - 84

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Abstract

Abstract Methylated and partially methylated cyclodextrin homo-and heterodimers linked by diamidosuccinic bridges were synthesised and their inclusion properties were evaluated using NMR and isothermic microcalorimetric measurements ITC. The selective binding of ligands, such as bisadamantyl derivatives, to the cavities of unprotected cyclodextrin dimers showed the equimolar formation of bidendate inclusion complexes (2: 2, two ligand guest ...