Fe (III) halides as effective catalysts in carbon-carbon bond formation: Synthesis of 1, 5-dihalo-1, 4-dienes, α, β-unsaturated ketones, and cyclic ethers

…, DD Díaz, JI Padrón, MA Ramírez…

Index: Miranda, Pedro O.; Diaz, David D.; Padron, Juan I.; Ramirez, Miguel A.; Martin, Victor S. Journal of Organic Chemistry, 2005 , vol. 70, # 1 p. 57 - 62

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Citation Number: 84

Abstract

Iron (III) halides have proven to be excellent catalysts in the coupling of acetylenes and aldehydes. When terminal acetylenes were used the main products obtained were 1, 5- dihalo-1, 4-dienes with (E, Z)-stereochemistry contaminated in some cases with (E)-α, β- unsaturated ketones. The former carbonyl derivatives were the sole products isolated when nonterminal aromatic alkynes were used. When homopropargylic alcohols were used, a ...