Reaction of InCl3 with various reducing agents: InCl3–NaBH4-mediated reduction of aromatic and aliphatic nitriles to primary amines

…, S Eagon, D Haddenham, B Singaram

Index: Saavedra, Jaime Z.; Resendez, Angel; Rovira, Alexander; Eagon, Scott; Haddenham, Dustin; Singaram, Bakthan Journal of Organic Chemistry, 2012 , vol. 77, # 1 p. 221 - 228

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Citation Number: 34

Abstract

While alternative methods of preparing dichloroindium hydride (HInCl2) via the in situ reduction of InCl3 using lithium amino borohydride (LAB) were explored, generation of HInCl2 from the reduction of InCl3 by sodium borohydride (NaBH4) was also re-evaluated for comparison. The reductive capability of the InCl3/NaBH4 system was found to be highly dependent on the solvent used. Investigation by 11B NMR spectroscopic analyses ...