Chinese Chemical Letters

Synthesis of 3-acylindoles via decarboxylative cross-coupling reaction of free (NH) indoles with α-oxocarboxylic acids

LJ Gu, JY Liu, LZ Zhang, Y Xiong, R Wang

Index: Gu, Li-Jun; Liu, Ji-Yan; Zhang, Li-Zhu; Xiong, Yong; Wang, Rui Chinese Chemical Letters, 2014 , vol. 25, # 1 p. 90 - 92

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Citation Number: 19

Abstract

A convenient and general method for acylation of free (N H) indoles via palladium-catalyzed decarboxylative cross-coupling reaction was developed. This process provided a useful method for the preparation of diverse 3-acylindoles in high yields utilizing a reaction with readily accessible reactants under mild conditions. ... A convenient method for the preparation of 3-acylindoles via palladium-catalyzed decarboxylative cross-coupling reaction of free (N H) indoles with ...