RSC Advances

Monobromomalononitrile: an efficient regioselective mono brominating agent towards active methylene compounds and enamines under mild conditions

S Pathak, A Kundu, A Pramanik

Index: Pathak, Sudipta; Kundu, Ashis; Pramanik, Animesh RSC Advances, 2014 , vol. 4, # 20 p. 10180 - 10187

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Citation Number: 4

Abstract

The potential of monobromomalononitrile (MBM) as a convenient source of cationic bromine in organic bromination reaction has been explored. Studies reveal that MBM can be a good substitute for N-bromosuccinimide (NBS) in various respects. Enamines and active methylene compounds bearing aromatic rings are selectively mono brominated on the vinylic and active methylene group respectively on reaction with MBM. This methodology ...