... 7) R. Breslow, J. Am. Chem. Soc., 80, 3719 (1958). N1 I—Electronic Library Service Page 2. 344 Vol. 17 (1969) The present paper describes the chemical synthesis of hydroxymethylthiamine. ... Page 4. 346 Vol. 17 (1969) large geminal coupling constant (]=15 cps). ...