Influence of steric crowding on the electrochemical reduction of substituted tertiary pyridylcarboxamides in aqueous acidic medium

M Largeron, N Auzeil, E Bacqué…

Index: Largeron, Martine; Auzeil, Nicolas; Bacque, Eric; Fleury, Maurice-Bernard Journal of the Chemical Society. Perkin Transactions 2, 1997 , # 3 p. 495 - 501

Full Text: HTML

Citation Number: 2

Abstract

In order to assess the influence of the steric crowding on the electrochemical reduction of pyridylcarboxamides, we have studied a series of tertiary aromatic or alicyclic pyridylcarboxamides. We have shown that increasing steric hindrance at the amide nitrogen led to the production of either tetrahydropyridine or aminomethylpyridine.