Tetrahedron

Metallo-phosphorylation of alkenes: a highly regioselective reaction of zirconocene–alkene complexes with chlorophosphate

C Lai, C Xi, W Chen, R Hua

Index: Lai, Chunbo; Xi, Chanjuan; Chen, Weixuan; Hua, Ruimao Tetrahedron, 2006 , vol. 62, # 26 p. 6295 - 6302

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Citation Number: 8

Abstract

Phosphorylation of unsaturated substrates is an attractive reaction for the synthesis of organophosphonates RP(O)(OR′) 2 that are useful intermediates in organic synthesis. 1, 1a, 1b, 1c, 1d and 1e Particularly interesting and challenging in the reaction are the simultaneous introduction of phosphonate and other functional groups to multiple carbon–carbon bonds. 2, 2a, 2b and 2c The metallo-phosphorylation is especially interesting, as it is a more versatile and elegant synthetic elaboration, ...