Acetohydroxamic acid: a new reagent for efficient synthesis of nitriles directly from aldehydes using Bi (OTf) 3 as the catalyst

…, VV Sairam, J Raveendra, KR Godala, C Narsaiah…

Index: Sridhar, Madabhushi; Reddy, Mallu Kishore Kumar; Sairam, Vangipuram Venkata; Raveendra, Jillella; Godala, Kondal Reddy; Narsaiah, Chinthala; Ramanaiah, Beeram China; Reddy, Cirandur Suresh Tetrahedron Letters, 2012 , vol. 53, # 27 p. 3421 - 3424

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Citation Number: 15

Abstract

Nitriles are important starting materials for the preparation of amines, amides, carboxylic acids, aldehydes, esters, and ketones 1 and they are also industrially important for the production of polymers, agrochemicals, pharmaceuticals, and dyes. 2 The classical methods for the preparation of nitriles include Kolbe nitrile synthesis, 3 ammoxidation of aldehydes, 4 hydrocyanation of alkenes, 5 Sandmeyer reaction of diazonium salts, 6 and Rosenmund–von Braun ...