Novel synthetic strategy of carbolines via palladium-catalyzed amination and arylation reaction

T Iwaki, A Yasuhara, T Sakamoto

Index: Iwaki, Takehiko; Yasuhara, Akito; Sakamoto, Takao Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 11 p. 1505 - 1510

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Citation Number: 147

Abstract

Four parent carbolines and the corresponding 5-or 9-methylsulfonyl derivatives were synthesized by the palladium-catalyzed intramolecular arylation reaction of ortho-bromo- substituted anilinopyridines which were prepared by the palladium-catalyzed amination reaction of iodobenzenes with aminopyridines. Carbazole and its 9-methylsulfonyl derivative were also synthesized by the same method.