Organic letters

Lewis acid assisted ring-closing metathesis of chiral diallylamines: An efficient approach to enantiopure pyrrolidine derivatives

Q Yang, WJ Xiao, Z Yu

Index: Yang, Qian; Xiao, Wen-Jing; Yu, Zhengkun Organic Letters, 2005 , vol. 7, # 5 p. 871 - 874

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Citation Number: 123

Abstract

Lewis acid assisted ring-closing olefin metathesis (RCM) of chiral diallylamines, using the second generation RCM ruthenium-based catalyst, leads to enantiopure pyrrolidine derivatives in 79-93% yields under very mild conditions. The scope of the olefin metathesis has been expanded.