A concise chemical synthesis of a fluorescent βGal-(1, 4)-S-βGlc-Cer derivative and its enzymatic elongation by glycosyltransferases

…, Y Yoshimura, NJ Dovichi, MM Palcic, O Hindsgaul

Index: Tanaka, Hidenori; Yoshimura, Yayoi; Dovichi, Norman J.; Palcic, Monica M.; Hindsgaul, Ole Tetrahedron Letters, 2012 , vol. 53, # 14 p. 1812 - 1815

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Citation Number: 6

Abstract

A straightforward chemical synthesis of lyso-lactosylceramide with the terminal galactose linked to glucose through a β-S-glycosidic bond is reported. The product is labeled on the amino-group with tetramethylrhodamine enabling its ultrasensitive detection in capillary ...