Molecules

IBS-Catalyzed Regioselective Oxidation of Phenols to 1, 2-Quinones with Oxone®

M Uyanik, T Mutsuga, K Ishihara

Index: Uyanik, Muhammet; Mutsuga, Tatsuya; Ishihara, Kazuaki Molecules, 2012 , vol. 17, # 7 p. 8604 - 8616

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Citation Number: 23

Abstract

Abstract We have developed the first example of hypervalent iodine (V)-catalyzed regioselective oxidation of phenols to o-quinones. Various phenols could be oxidized to the corresponding o-quinones in good to excellent yields using catalytic amounts of sodium salts of 2-iodobenzenesulfonic acids (pre-IBSes) and stoichiometric amounts of Oxone® as a co-oxidant under mild conditions. The reaction rate of IBS-catalyzed oxidation under ...