Tetrahedron

Versatility of Weinreb amides in the Knorr pyrrole synthesis

A Alberola, AG Ortega, ML Sádaba, C Sañudo

Index: Alberola, Angel; Ortega, Alfonso Gonzalez; Sadaba, M. Luisa; Sanudo, Carmen Tetrahedron, 1999 , vol. 55, # 21 p. 6555 - 6566

Full Text: HTML

Citation Number: 81

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Departmento de Química Orgánica, Facultad de Ciencias, Universidad de Valladolid, 47005 Valladolid, Spain. ... N-Methoxy-N-methyl-α-enaminocarboxamides were prepared starting from enamines and Weinreb α-aminoamides. Their reaction with oganometallic compounds ...

 Related Synthetic Route
2-(2-cyano-1-methylvinylamino)-N-methoxy-N-methylpropionamide Structure

231609-59-9

2-(2-cyano-1-me...

~92%

2,5-dimethyl-1H-pyrrole-3-carbonitrile Structure

26187-29-1

2,5-dimethyl-1H...

2-(2-cyano-1-methylvinylamino)-N-methoxy-N-methylpropionamide Structure

231609-59-9

2-(2-cyano-1-me...

~27%

1H-Pyrrole-3-carboxaldehyde,2,5-dimethyl- Structure

2199-63-5

1H-Pyrrole-3-ca...

2,5-dimethyl-1H-pyrrole-3-carbonitrile Structure

26187-29-1

2,5-dimethyl-1H...

Ethyl (2Z)-3-amino-2-butenoate Structure

626-34-6

Ethyl (2Z)-3-am...

~%

1H-Pyrrole-3-carboxylicacid, 2,5-dimethyl-4-phenyl-, ethyl ester Structure

16206-31-8

1H-Pyrrole-3-ca...

Phenyllithium Structure

591-51-5

Phenyllithium

ethyl 3-(1-(N-methoxy-N-methylcarbamoyl)ethylamino)crotonate Structure

231609-65-7

ethyl 3-(1-(N-m...

~%

1H-Pyrrole-3-carboxylicacid, 2,5-dimethyl-4-phenyl-, ethyl ester Structure

16206-31-8

1H-Pyrrole-3-ca...

METHYLLITHIUM Structure

917-54-4

METHYLLITHIUM

ethyl 3-(1-(N-methoxy-N-methylcarbamoyl)ethylamino)crotonate Structure

231609-65-7

ethyl 3-(1-(N-m...

~80%

ethyl 2,4,5-trimethyl-1H-pyrrole-3-carboxylate Structure

2199-54-4

ethyl 2,4,5-tri...

2-(2-cyano-1-methylvinylamino)-N-methoxy-N-methylpropionamide Structure

231609-59-9

2-(2-cyano-1-me...

~34%

1H-Pyrrole-3-carboxaldehyde,2,5-dimethyl- Structure

2199-63-5

1H-Pyrrole-3-ca...

2,5-dimethyl-1H-pyrrole-3-carbonitrile Structure

26187-29-1

2,5-dimethyl-1H...

2-(2-acetyl-1-methylvinylamino)-N-methoxy-N-methylacetamide Structure

231609-66-8

2-(2-acetyl-1-m...

~60%

1-(2-METHOXY-PHENYL)-5-OXO-PYRROLIDINE-3-CARBOXYLICACID Structure

6009-46-7

1-(2-METHOXY-PH...

Fluoral-P Structure

1118-66-7

Fluoral-P

~%

1-(2-METHOXY-PHENYL)-5-OXO-PYRROLIDINE-3-CARBOXYLICACID Structure

6009-46-7

1-(2-METHOXY-PH...

Ethyl (2Z)-3-amino-2-butenoate Structure

626-34-6

Ethyl (2Z)-3-am...

~%

1H-Pyrrole-3-carboxylicacid, 2-methyl-4-phenyl-, ethyl ester Structure

3274-63-3

1H-Pyrrole-3-ca...

Phenyllithium Structure

591-51-5

Phenyllithium

ethyl 3-((N-methoxy-N-methylcarbamoyl)methylamino)crotonate Structure

231609-63-5

ethyl 3-((N-met...

~%

1H-Pyrrole-3-carboxylicacid, 2-methyl-4-phenyl-, ethyl ester Structure

3274-63-3

1H-Pyrrole-3-ca...

METHYLLITHIUM Structure

917-54-4

METHYLLITHIUM

2-(2-acetyl-1-methylvinylamino)-N-methoxy-N-methylacetamide Structure

231609-66-8

2-(2-acetyl-1-m...

~9%

3-Acetyl-2,4-dimethylpyrrole Structure

2386-25-6

3-Acetyl-2,4-di...

ethyl 3-((N-methoxy-N-methylcarbamoyl)methylamino)crotonate Structure

231609-63-5

ethyl 3-((N-met...

~68%

Ethyl 2-methylpyrrole-3-carboxylate Structure

936-12-9

Ethyl 2-methylp...


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