Isolation and synthesis of flavonols and comparison of their antioxidant activity

A Hasan, A Sadiq, A Abbas, E Mughal…

Index: Hasan, Aurangzeb; Sadiq; Abbas; Mughal; Khan, Khalid M.; Ali, Muhammad Natural Product Research, 2010 , vol. 24, # 11 p. 995 - 1003

Full Text: HTML

Citation Number: 10

Abstract

Phytochemical investigation of the leaves of Astragalus beckari yielded four flavonol aglycones, namely kaempferol, quercetin, 5-deoxy kaempferol and fisitin. These isolated compounds were then synthesised in the laboratory using the Algar–Flyn–Oyamad reaction. Antioxidant activity of both the isolated and synthesised flavonoids was compared using the 1, 1-diphenyl-2-picrylhydrazyl (DPPH) assay method. The isolated flavonoids were found ...