Papain-Assisted Resolution of Natural and Xenobiotic α-Amino Acid

JL Moriniere, B Danree, J Lemoine…

Index: Moriniere, J. L.; Danree, B.; Lemoine, J.; Guy, A. Synthetic Communications, 1988 , vol. 18, # 4 p. 441 - 444

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Citation Number: 19

Abstract

Abstract A new and convenient method for the preparation of pure enantiomers of α-amino acids is described. Industrial papain, catalyzes the synthesis of LZ-amino acid ethyl esters in ethanolic medium, with good yields. These esters are obtained from DL-Z-amino acids with 100% optical purity. Unreactive DZ-amino acids are readily isolated from reaction medium. Physical constants of natural and xenobiotic LZ-amino acid esters and DZ-amino acids ...