A divergent synthesis of three sulfate derivatives of lamellarin α, namely, lamellarin α 13- sulfate (2), 20-sulfate (1), and 13, 20-disulfate (4) has been achieved via a common intermediate (6) in which 13-OH and 20-OH of the lamellarin core are differentially protected by MOM and benzyl groups, respectively. Compound (6) in turn was prepared using sequential Suzuki-Miyaura coupling of 3, 4-dihydroxypyrrole bistriflate (7) as a key ...
