(Pentamethylcyclopentadienyl) Iridium Dichloride Dimer {[IrCp* Cl2] 2}: A Novel Efficient Catalyst for the Cycloisomerizations of Homopropargylic Diols and N?? …

…, M Malacria, JP Goddard, L Fensterbank

Index: Benedetti, Erica; Simonneau, Antoine; Hours, Alexandra; Amouri, Hani; Penoni, Andrea; Palmisano, Giovanni; Malacria, Max; Goddard, Jean-Philippe; Fensterbank, Louis Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 1908 - 1912

Full Text: HTML

Citation Number: 20

Abstract

Abstract (Pentamethylcyclopentadienyl) iridium dichloride dimer {[IrCp* Cl 2] 2}-catalyzed hydroalkoxylation of bis-homopropargylic alcohols provides an efficient access to dioxabicyclo [2.2. 1] ketals. The cycloisomerizations proceed under mild conditions, with low catalytic loadings and short reaction times. This new protocol involving an Ir (III) catalyst also promoted the cycloisomerization of nitrogen-tethered 1, 6-enynes to give azabicyclo [4.1. ...