Abstract Syntheses of novel 15-thia-11, 13-diazasteroidal skeleton IV and its D-homo analogues are described. Meso-ionic derivatives of IV were also synthesized. Antidepressive activities of these compounds and their precursors were screened. D- Dihomothiadiazasteroid IX and 3, 4, 5, 6-tetrahydrobenzo [h] quinazoline-4-thione (V) exhibited antireserpine action.
![4-chloro-5,6-dihydrobenzo[h]quinazoline Structure](https://image.chemsrc.com/caspic/015/57711-36-1.png)
![5,6-dihydro-1H-benzo[h]quinazoline-4-thione Structure](https://image.chemsrc.com/caspic/449/113331-26-3.png)