The protection of hydroxyl groups

WE Parham, EL Anderson

Index: Parham; Anderson Journal of the American Chemical Society, 1948 , vol. 70, p. 4187

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Citation Number: 131

Abstract

It has been shown, principally by Gilman and his co-workers, 2 that metalation of phenols and phenolic ethers constitutes an important step in the synthetic route to certain organic compounds. Metalation of phenolic ethers generally yields fewer isomers than does metalation of the corresponding phenols3; however, the use of the ether as a protecting group has the disadvantage that the product obtained subsequent to reaction is still an ...