Tetrahedron Letters

A novel synthesis of (E)-3, 7-dimethyl-2-octene-1, 8-diol secreted by the african monarch using the ring-opening reaction of α-methyl-β-propiolactone

T Fujisawa, T Sato, T Kawara, A Noda

Index: Fujisawa, Tamotsu; Sato, Toshio; Kawara, Tatsuo; Noda, Atsunari Tetrahedron Letters, 1982 , vol. 23, # 31 p. 3193 - 3194

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Citation Number: 15

Abstract

Abstract The regioselective ring-opening reaction of α-methyl-β-propiolactone with 3, 3- ethylene-dioxybutylmagnesium bromide in the presence of copper (I) catalyst afforded 2- methyl-6-oxoheptanoic acid, which was easily converted into (E)-3, 7-dimethyl-2-2-octene-1, 8-diol in good yield.