Optimization of small-molecule inhibitors of influenza virus polymerase: from thiophene-3-carboxamide to polyamido scaffolds

S Lepri, G Nannetti, G Muratore…

Index: Offermann; Eger; Roth Archiv der Pharmazie, 1981 , vol. 314, # 2 p. 168 - 175

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Citation Number: 18

Abstract

... Volume: Page: Digital Object Identifier (DOI). ... 5, I, 2, CF 3, Me, 43.0 ± 9.9, 63.0 ± 9.9, 100.7 ± 14.0, >250, >250. 6, I, 2, CF 3, OMe, 135.3 ± 14.2, ND, ND, 40.4 ± 3.3, 51.3 ± 3.1. 7, II, 2, CF 3, H, 7.5 ± 0.7, 9.2 ± 2.3, 23.7 ± 9.1, >250, >250. 8, III, 2, >200, ND, ND, >250, 45.2 ± 3.1. ...