Tetrahedron

Oligonucleotide synthesis in terms of a novel type of polymer-support: a cellulose acetate functionalized with 4-(2-hydroxyethylsulfonyl) dihydrocinnamoyl substituent

…, Y Hasegawa, I Masuda, Y Ishido, K Watanabe, I Hirao…

Index: Kamaike, Kazuo; Hasegawa, Yoshihiro; Masuda, Izumi; Ishido, Yoshiharu; Watanabe, Kimitsuna; Hirao, Ichiro; Miura, Kin-Ichiro Tetrahedron, 1990 , vol. 46, # 1 p. 163 - 184

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Citation Number: 6

Abstract

The title polymer-support was proved to be useful practically in oligonucleotide synthesis which is characterized by the points of excel lence involved in both liquid-and solid-phase approaches ie being able to perform a nucleotide and/or oligonucleotide unit introduction in pyridine in a homogeneous state and to isolate the resulting polymer-support bearing the resulting oligonucleotide chain by pouring the resulting solution into an excess volume of ...