Synthesis, biological evaluation and molecular modelling of N-heterocyclic dipeptide aldehydes as selective calpain inhibitors

MA Jones, JD Morton, JM Coxon, SB McNabb…

Index: Bioorganic and Medicinal Chemistry, , vol. 16, # 14 p. 6911 - 6923

Full Text: HTML

Citation Number: 14

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry. Volume 16, Issue 14, 15 July 2008, Pages 6911–6923. ... 1 Over-activation of calpain is central to a number of medical conditions associated with cellular damage. ...