Carbon??nitrogen bond formation in cyclisation by deoxygenation, thermolysis or photolysis of phenylimidazo [1, 2??a][1, 8] naphthyridines

A Gueiffier, Y Blache, H Viols, JP Chapat…

Index: Gueiffier, A.; Blache, Y.; Viols, H.; Chapat, J. P.; Chavignon, O.; et al. Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 2 p. 283 - 287

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Citation Number: 8

Abstract

Abstract Triethyl phosphite deoxygenation of 2-(2-nitrophenyl) imidazo [1, 2-a][1, 8] naphthyridine (3) led to the C-insertion to give the indoloimidazonaphthyridine 5. Our attempt to promote the N-insertion by blocking the C-3 position failed. Triethyl phosphite deoxygenation of 1-nitroso-2-(4-fluorophenyl) imidazo [1, 2-a][1, 8]-naphthyridine (12) led to the corresponding amine structure (15). Thermolysis and photolysis of 6, 8-dimethyl-2-(2- ...