Chemische Berichte

Heterocyclische β??Enaminoester, 27. Synthese von heterokondensierten 6H??1, 3??Oxazin??6??onen aus N??Acylenaminoestern im system Triphenylphosphan/ …

D Achakzi, M Ertas, R Appel, H Wamhoff

Index: Achakzi, Darwizah; Ertas, Muemtaz; Appel, Rolf; Wamhoff, Heinrich Chemische Berichte, 1981 , vol. 114, # 9 p. 3188 - 3194

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Citation Number: 8

Abstract

A simple ring closure reaction of N-acylenamino esters (1 b, e, 2, 3a-f, 7) in the system triphenyl-phosphane/hexachloroethane/triethylamine is described proceeding with high yields. Under chlorinating 3-ester cleavage heterocondensed 6H-1, 3-oxazin-6-ones 4a-f, 5, 6b, e, 8, 9 are formed (UV, IR, NMR, MS).

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ethyl 2-benzamido-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate Structure

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ethyl 2-benzami...

~93%

5,6,7,8-Tetrahydro-2-phenyl-4H-[1]benzothieno[2,3-d][1,3]oxazin-4-one Structure

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5,6,7,8-Tetrahydro-2-phenyl-4H-[1]benzothieno[2,3-d][1,3]oxazin-4-one Structure

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2,6-Diphenyl-4H,8H-thieno<2,3-d:4,5-d'>bis<1,3>oxazin-4,8-dion Structure

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2-Isobutyrylami...

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ethyl 5-amino-2...

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