Etude de la réaction de cyclisation des halohydrines-1, 2 ethyl phosphonates de diéthyle pour l'obtention de l'époxy-1, 2 éthyl phosphonate de diéthyle

G Sturtz, A Pondaven-Raphalen

Index: Sturtz, G.; Pondaven-Raphalen, A. Phosphorus and Sulfur and the Related Elements, 1984 , vol. 20, p. 35 - 48

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Citation Number: 10

Abstract

Abstract Here we report on the synthesis of the diethyl 1, 2-epoxyethylphosphonate 1 from diethyl 1-halogeno 2-hydroxyethylphosphonates 4a and 4b. The halohydrins were prepared by hypohalogenation of the diethyl vinylphosphonate and their structures confirmed by 31P. 1H and 13C NMR spectroscopy. The epoxidation cyclisation was studied using a variety of bases (HNa. KOH, EtO−, K2CO3) and solvents (THF, EtOH, MeOH). In aprotic solvents, ...