Contrasteric regiochemical incorporation of stannylacetylenes in the benzannulation reaction

S Chamberlin, ML Waters, WD Wulff

Index: Chamberlin, Steven; Waters, Marcey L.; Wulff, William D. Journal of the American Chemical Society, 1994 , vol. 116, # 7 p. 3113 - 3114

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Citation Number: 33

Abstract

The high degree of regioselectivity in the benzannulation reaction of &unsaturated Fischer carbene complexes with terminal alkynes is one of the more attractive aspects of this synthetically important reaction. 2 It has long been established that the major contributor to the regioselectivity of this reaction is the steric differential between the two substituents on the alkyne which leads to the preferential formation of the phenol 5 where the larger ...