A methodology for the determination of the stereoselectivity in the addition of thiols to indene is described. The chemical method employs an S-deuterio thiol, the thermal elimination reaction of the sulfoxides derived from the adducts, and the determination of the D content in the resulting indene. The preferred spectroscopic method employs 1, 1, 3-trideuterioindene and the LIS technique in the NMR analysis of the sulfones derived from the thiol-olefin ...
