Attempts at new synthesis of 5, 11??Dihydro??6H??pyrido [2, 3??b][1, 4] benzodiazepin??6??one

M Oklobdžija, G Comisso, E Decorte…

Index: Oklobdzija; Comisso; Decorte; et al. Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 5 p. 1335 - 1338

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Citation Number: 2

Abstract

Abstract Attempting some new approaches to 5, 11-dihyro-6H-pyrido [2, 3-b][1, 4] benzodiazepin-6-one (6), compounds 8, 10 and 11 were prepared. Ring enlargement of 4 into 6 failed, as well as condensation of 10 and 11 into ID, which is the potential precursor of pirenzepin (11-[2′-(4 ″-methylpiperazin-1 ″-yl)] acetyl derivative of 6) via an envisaged intramolecular Diels-Alder reaction. Model compounds 5 and 13 were prepared and their ...