Abstract A synthetic protocol for the direct synthesis of N-(hydroxyalkyl) cinnamamides from cinnamates and aminoalcohols in the presence of sodium carbonate as the base is presented. A wide variety of N-(hydroxyalkyl) cinnamamides were isolated in up to 99% yields. The reaction is highly regioselective and yields only N-acylated products by 1, 2- addition of aminoalcohols to cinnamates.
