Palladium (II)??Catalyzed Hydration of Alkynylphosphonates to β??Ketophosphonates

…, P Luo, G Tang, Y Gao, P Xu, Y Zhao

Index: Li, Xiubin; Hu, Gaobo; Luo, Ping; Tang, Guo; Gao, Yuxing; Xu, Pengxiang; Zhao, Yufen Advanced Synthesis and Catalysis, 2012 , vol. 354, # 13 p. 2427 - 2432

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Citation Number: 41

Abstract

Abstract A highly efficient palladium (II)-catalyzed hydration of a wide range of alkynylphosphonates to the corresponding β-ketophosphonates has been developed to give high yields at 80 C in 1, 4-dioxane, with no acidic or alkaline cocatalysts required. The described catalytic system should provide an efficient alternative to highly toxic mercury- catalyzed methodologies and be useful in synthetic programs.