Tetrahedron: Asymmetry

Enzymatic synthesis of optically active 2-carbamoyl-oxymethyl-1, 4-dihydropyridines,(R)-(+)-and (S)-(−)-NB 818

H Ebiike, K Maruyama, K Achiwa

Index: Ebiike, Hirosato; Maruyama, Kaori; Achiwa, Kazuo Tetrahedron: Asymmetry, 1992 , vol. 3, # 9 p. 1153 - 1156

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Citation Number: 15

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Racemic dihydropyridines were resolved by enzyme-catalyzed hydrolysis in an organic solvent saturated with water. The chiral derivatives obtained were converted to (S)- and (R)-NB 818. ... Sourse of chirality: Lipase AH-SE from Pseudomonas sp. ... Sourse of chirality: Lipase ...