Synlett

An Efficient One-Pot Synthesis of ω-Hydroxy Ketones from Lactones

SB Yang, FF Gan, GJ Chen, PF Xu

Index: Yang, Shao-Bo; Gan, Feng-Feng; Chen, Guo-Ju; Xu, Peng-Fei Synlett, 2008 , # 16 p. 2532 - 2534

Full Text: HTML

Citation Number: 9

Abstract

Abstract An efficient and convenient one-pot strategy was developed for the synthesis of 1- hydroxydodecan-6-one, an important precursor for total synthesis of sphingofungin F. A series of ω-hydroxy ketones were prepared from readily available lactones using this one- pot reaction.