Tetrahedron

Determining the scope of the lanthanide mediated, sequential hydroamination/C–C cyclization reaction: formation of tricyclic and tetracyclic aromatic nitrogen …

GA Molander, SK Pack

Index: Molander, Gary A.; Pack, Shawn K. Tetrahedron, 2003 , vol. 59, # 52 p. 10581 - 10591

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Citation Number: 32

Abstract

The scope of the lanthanide mediated, sequential hydroamination/C–C cyclization reaction was determined for the formation of tricyclic and tetracyclic aromatic nitrogen heterocycles. An array of ring sizes was explored to determine the diastereoselectivity. The electronic characteristics of the aromatic ring was also varied to determine how it affected the cascade reaction. It was found that the benzo [a] quinolizine and the pyrido [2, 1, a] isoindolizine ...