Acetylcyanation of Aldehydes with Acetone Cyanohydrin and Isopropenyl Acetate by Cp* 2Sm (thf) 2

…, A Fujii, Y Nakano, S Sakaguchi, Y Ishii

Index: Kawasaki, Yumi; Fujii, Akiko; Nakano, Yasushi; Sakaguchi, Satoshi; Ishii, Yasutaka Journal of Organic Chemistry, 1999 , vol. 64, # 11 p. 4214 - 4216

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Citation Number: 27

Abstract

There are a number of potentially useful methods for hydrocyanation using various cyanating reagents such as hydrogen cyanide, 1 alkali or alkaline-earth metal cyanides, 2 organoaluminum cyanides, 3 organosilicone cyanides, 4 and acetone cyanohydrin5 which can generate cyanide ion in the presence of a base. Among them, the hydrocyanation using acetone cyanohydrin is known as the Nazarov method. 5 However, the reactivity of ...