Activation of sulfonate ester based matrix metalloproteinase proinhibitors by hydrogen peroxide

KB Daniel, JLM Jourden, KE Negoescu…

Index: Journal of Biological Inorganic Chemistry, , vol. 16, # 2 p. 313 - 323

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Citation Number: 11

Abstract

... JBIC Journal of Biological Inorganic Chemistry. ... Under the appropriate biological stimulus, the proinhibitor can be activated, releasing the MMPi, thereby allowing for localized delivery and inhibition ... 7.28 (dt, J 1 = 6.9 Hz, J 2 = 2.3 Hz, 1H), 6.52 (d, J = 9.8 Hz, 1H), 6.15 (t, J = 7.5 Hz ...