Synlett

Reactions of Cyclopropyl Aryl Ketones with Sulfonamides Mediated by Zr (OTf) 4: Cascade Preparation of 5-Aryl-3, 4-dihydro-2H-pyrrole

M Shi, YH Yang, B Xu

Index: Shi, Min; Yang, Yong-Hua; Xu, Bo Synlett, 2004 , # 9 p. 1622 - 1624

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Citation Number: 7

Abstract

Abstract We found that the Lewis acid Zr (OTf) 4 can effectively promote the ring-opening reaction of cyclopropyl aryl ketones with sulfonamides. By controlling the reaction conditions, we could obtain the ring-opened products 3 and the cyclized products 5 in