New Journal of Chemistry

Synthesis of macrocyclic ketones exploiting palladium-catalyzed activation of carboxylic acids as an enabling step

AR Kapdi, IJS Fairlamb

Index: Kapdi, Anant R.; Fairlamb, Ian J. S. New Journal of Chemistry, 2013 , vol. 37, # 4 p. 961 - 964

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Citation Number: 4

Abstract

The novel synthesis of macrocyclic arylketones via palladium-catalyzed cross-coupling of arylboronic acids and carboxylic acids, activated by the treatment with di (N-succinimidyl) carbonate, is disclosed. This allows the high yielding synthesis of various functionalized