11-Alkoxy-dibenzo [b, e] azepin-6-ones with anti-convulsant activity

V Pestellini, G Viti, R Nannicini, F Borsini…

Index: Pestellini; Viti; Nannicini; Borsini; Furio European Journal of Medicinal Chemistry, 1988 , vol. 23, # 5 p. 473 - 476

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Citation Number: 4

Abstract

Abstract Data relative to the synthesis and anti-convulsant properties of new 5, 6-dihydro- dibenzo [b, e] azepin-6-ones are presented. Structure-activity relationships of various derivatives substituted in positions 5 and 11, as well as the importance of the steric hindrance of the substituents on biological activity are shown.