Organic letters

Copper-promoted reductive coupling of aryl iodides with 1, 1, 1-trifluoro-2-iodoethane

S Xu, HH Chen, JJ Dai, HJ Xu

Index: Xu, Song; Chen, Huan-Huan; Dai, Jian-Jun; Xu, Hua-Jian Organic Letters, 2014 , vol. 16, # 9 p. 2306 - 2309

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Citation Number: 18

Abstract

An efficient Cu-promoted reductive coupling of aryl iodides with 1, 1, 1-trifluoro-2-iodoethane has been developed. This reaction could occur in good yields under milder conditions as compared with previous studies. The reaction tolerated nitro, formyl, ester, ether, carbonyl, sulfonyl, and even azo groups.