Di (uracilyl) aryl methanes and their homologues, 1, ω-bis [di (uracilyl) methyl] benzenes, have been synthesized in good yields through the HBr–acetic acid catalyzed condensation of 1-alkyl-/1, 3-dialkyluracil derivatives with readily available aryl aldehydes and dialdehydes.
[McCarthy, Orla; Musso-Buendia, Alex; Kaiser, Marcel; Brun, Reto; Ruiz-Perez, Luis M.; Johansson, Nils Gunnar; Pacanowska, Dolores Gonzalez; Gilbert, Ian H. European Journal of Medicinal Chemistry, 2009 , vol. 44, # 2 p. 678 - 688]