It has been observed that the hydrogenolytic opening of 2-isoxazolines depends on the substituents present in positions 3 and 5. The hydrogenolysis on 10% Pd/C of 2- isoxazolines, substituted in position 3 with carbonyl or carboxyl groups and in position 5 with an aromatic group, gives oximes, in contrast to other isoxazoline derivatives. From the 5-aryl- 2-isoxazolines it is possible to obtain aminoalcohols in ethanol and oximes in acetic acid.
