Palladium??Catalyzed Coupling of Propargylic Carbonates with N??Tosylhydrazones: Highly Selective Synthesis of Substituted Propargylic N??Sulfonylhydrazones and …

…, S Ali, KG Ji, PX Zhou, XY Liu, YM Liang

Index: Chen, Zi-Sheng; Duan, Xin-Hua; Wu, Lu-Yong; Ali, Shaukat; Ji, Ke-Gong; Zhou, Ping-Xin; Liu, Xue-Yuan; Liang, Yong-Min Chemistry - A European Journal, 2011 , vol. 17, # 25 p. 6918 - 6921

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Citation Number: 42

Abstract

The reaction of propargylic compounds with nucleophiles catalyzed by palladium is one of the most successful and reliable methods in organic synthesis.[1] The key step in these reactions is the formation of an allenyl-or π-propargylpalladium complex (an equilibrium process) by decarboxylation, which undergoes further reactions with other nucleophiles to afford different kinds of allene, alkene, alkyne, and enyne derivatives.[1] In sharp contrast, ...